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Shortages of these medications have been a concern as well

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doi: 10.1016/j.mcna.2017.08.012

We demonstrated that in GLUTag cells, a high glucose level with L-glutamine stimulates GLP-1 secretion through a synergistic effect rather than cAMP amplification, and that a high glucose level potentiates L-glutamine-Gs activation in GLP-1 secretion